Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | GAA | P10253 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.62 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217480 | 0.88 | MAPT (1.00) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL29388147 | 0.88 | MAPT (1.00) | MAPTGAAKDM4EALDH1A1MEN1 | |
| Sulfuric Acid SCHEMBL31174161 | 0.87 | MAPT (0.58) | MAPTGAAKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL29809096 | 0.86 | MAPT (0.95) | MAPTGAAKDM4EALDH1A1MEN1 | |
| Methane SCHEMBL4054340 | 0.86 | MAPT (0.95) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL6576141 | 0.86 | MAPT (0.95) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL9396742 | 0.84 | MAPT (0.91) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL9396738 | 0.84 | MAPT (0.91) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL4607773 | 0.81 | MAPT (0.86) | MAPTGAAKDM4EALDH1A1MEN1 | |
| Diphenylamine SCHEMBL1008716 | 0.79 | HSD17B10 (0.67) | MAPTGAAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416363-B1 | Modification of Polyarylenesulfides | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0416363-A2 | Modification of Polyarylenesulfides | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |