SCHEMBL6576148

SCHEMBL6576148

CN(C)C(CC(=O)O)SCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.43
CPA1 P15085 2/20 0.43
CPB1 P15086 1/20 0.43
CPA3 P15088 1/20 0.43
CPB2 Q96IY4 1/20 0.43
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2C9 P11712 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
AKR1B1 P15121 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8668132 0.98 CYP2C19 (0.42) CYP2C19CPA1CPB1CPA3CPB2
SCHEMBL6574182 0.84 SLC6A3 (0.45) POLBSMN1; SMN2PPARGPPARAL3MBTL1
SCHEMBL6578366 0.83 CYP2C19 (0.49) CYP2C19CPA3POLBSMN1; SMN2PPARG
SCHEMBL6577590 0.83 CYP2C19 (0.43) CYP2C19CPA1CPB1CPA3CPB2
SCHEMBL6576409 0.82 MEN1 (0.55) CYP2C19SMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL27862584 0.79 PPARG (0.48) CYP2C19CPA1CPB1CPA3CPB2
SCHEMBL27878876 0.76 CYP2C19 (0.46) CYP2C19CPA1CPB1CPA3CPB2
SCHEMBL7540831 0.75 CYP2C19 (0.63) CYP2C19CPA1CPB1CPA3CPB2
SCHEMBL6467489 0.75 CYP2C19 (0.46) CYP2C19CPA1CPB1CPA3CPB2
Hydrochloric Acid SCHEMBL6467921 0.74 IDO1 (0.45) CYP2C19CPA1CPB1CPA3CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0870762-B1 NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP SANTEN PHARMACEUTICAL CO LTD (JP) 2004-04-28 EP disclosed
EP-0870762-A1 NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP SANTEN PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed