Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CPA3 | P15088 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576148 | 0.83 | CYP2C19 (0.43) | CYP2C19CPA3NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8668132 | 0.82 | CYP2C19 (0.42) | CYP2C19CPA3MAPTKDM4AKDM4C | |
| SCHEMBL27878944 | 0.80 | CYP2C19 (0.51) | CYP2C19CPA3KEAP1MAPTRXFP1 | |
| SCHEMBL6574182 | 0.75 | SLC6A3 (0.45) | NPC1RAB9ASMN1; SMN2SLC6A3PPARG | |
| SCHEMBL21214617 | 0.73 | CPA3 (0.57) | CPA3KEAP1MAPTFFAR1NAALAD2 | |
| SCHEMBL6576409 | 0.73 | MEN1 (0.55) | CYP2C19MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20395792 | 0.72 | CYP2C19 (0.63) | CYP2C19CPA3KEAP1MAPTRXFP1 | |
| SCHEMBL3713575 | 0.72 | MAPT (0.47) | CYP2C19CPA3KEAP1MAPTRXFP1 | |
| SCHEMBL22612314 | 0.71 | MAPT (0.50) | CYP2C19CPA3KEAP1MAPTRXFP1 | |
| SCHEMBL6577590 | 0.71 | CYP2C19 (0.43) | CYP2C19CPA3SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870762-B1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| EP-0870762-A1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |