⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576161 | 0.78 | THRB (0.32) | — | |
| SCHEMBL20377369 | 0.71 | — | — | |
| SCHEMBL28384973 | 0.71 | — | — | |
| SCHEMBL4410111 | 0.69 | — | — | |
| SCHEMBL331977 | 0.67 | TDP1 (0.31) | — | |
| SCHEMBL10999183 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL29259016 | 0.65 | — | — | |
| Butane SCHEMBL17061028 | 0.63 | — | — | |
| SCHEMBL4487114 | 0.63 | — | — | |
| SCHEMBL1191430 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653439-B1 | Stabilized oligonucleotids and the use thereof | AVENTIS PHARMA GMBH (DE) | 2004-04-28 | — | — | EP | claimed |
| US-6348312-B1 | OLIGONUCLEOTIDE HAVING LENGTH OF 6-100 NUCLEOTIDES, WHEREIN AT LEAST ONE NON-TERMINAL PYRIMIDINE NUCLEOSIDE IS MODIFIED, AND ALSO 5' AND/OR 3' ENDS ARE MODIFIED, BY REPLACEMENT OF 3' AND/OR 5' PHOSPHODIESTER BRIDGE BY PHOSPHOROTHIOATE BRIDGE | HOESCHT AKTIENGESELLSCHAFT (DE) | 2002-02-19 | — | — | US | disclosed |