SCHEMBL6576161

SCHEMBL6576161

CC(C)(O[PH](=O)O)C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28244105 0.78
SCHEMBL17696695 0.78
SCHEMBL6576156 0.78
SCHEMBL17923493 0.76
SCHEMBL5426167 0.75
SCHEMBL28384976 0.74
SCHEMBL17061029 0.71
SCHEMBL748440 0.71
SCHEMBL331834 0.71
Ethyl Chloride SCHEMBL10612356 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0653439-B1 Stabilized oligonucleotids and the use thereof AVENTIS PHARMA GMBH (DE) 2004-04-28 EP claimed
US-6348312-B1 OLIGONUCLEOTIDE HAVING LENGTH OF 6-100 NUCLEOTIDES, WHEREIN AT LEAST ONE NON-TERMINAL PYRIMIDINE NUCLEOSIDE IS MODIFIED, AND ALSO 5' AND/OR 3' ENDS ARE MODIFIED, BY REPLACEMENT OF 3' AND/OR 5' PHOSPHODIESTER BRIDGE BY PHOSPHOROTHIOATE BRIDGE HOESCHT AKTIENGESELLSCHAFT (DE) 2002-02-19 US disclosed