Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 5/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453934 | 0.83 | KIF11 (0.44) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL27830682 | 0.83 | MAPK1 (0.44) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL11667136 | 0.83 | MAPT (0.44) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL241852 | 0.82 | KIF11 (0.49) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL29376743 | 0.82 | KIF11 (0.49) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL28876207 | 0.81 | KIF11 (0.47) | MAPK1MAPTNPSR1KIF11GABRP | |
| Ammonia Solution, Strong SCHEMBL28918843 | 0.81 | KIF11 (0.47) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL11662631 | 0.81 | MAPT (0.43) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL28879427 | 0.77 | KIF11 (0.51) | MAPK1MAPTNPSR1KIF11GABRP | |
| SCHEMBL4422677 | 0.75 | AHR (0.38) | MAPK1MAPTKIF11GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453802-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050086-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2003-06-19 | — | — | WO | disclosed |