Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.69 |
| ▸ | PPARG | P37231 | 6/20 | 0.66 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | CDC25B | P30305 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575957 | 0.90 | PPARA (0.70) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL6578294 | 0.90 | PPARA (0.73) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL6577913 | 0.90 | PPARA (0.73) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL12130757 | 0.88 | PPARA (0.85) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL14058699 | 0.83 | PPARA (0.78) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL14058698 | 0.83 | PPARA (0.78) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL828674 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL1132901 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL17051 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSRAB9AKLK7 | |
| SCHEMBL6577875 | 0.83 | PPARA (0.47) | PPARAPPARGCTSSRAB9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870762-B1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0870762-A1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |