SCHEMBL6576457

SCHEMBL6576457

N#CC(CC1CCCCC1)N=NC(C#N)CC1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSK P43235 10/20 0.37
CTSL P07711 6/20 0.37
CTSB P07858 6/20 0.37
CTSH P09668 4/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
HSP90AB1 P08238 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9491594 0.98 CTSK (0.35) CTSKCTSLCTSBCTSHHSP90AB1
SCHEMBL5850586 0.89
SCHEMBL27437240 0.75 CTSK (0.39) CTSKCTSLCTSBCTSHHSP90AB1
SCHEMBL29278682 0.75 CTSK (0.39) CTSKCTSLCTSBCTSHHSP90AB1
SCHEMBL27534752 0.73 KDM4E (0.38) CTSKCTSLCTSBCTSH
SCHEMBL21211687 0.73 KDM4E (0.38) CTSKCTSLCTSBCTSH
SCHEMBL27437457 0.71 CTSK (0.45) CTSKCTSLCTSBCTSH
SCHEMBL4395112 0.71 CTSK (0.37) CTSKCTSLCTSBCTSHHSP90AB1
SCHEMBL3992964 0.71 CTSK (0.40) CTSKCTSLCTSBCTSHHSP90AB1
SCHEMBL13567828 0.68 CTSK (0.42) CTSKCTSLCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915134-B1 Thermoplastic elastomer with high resistance, elasticity and good paintability and high impact resistant polymer blends prepared therefrom BOREALIS GMBH (AT) 2004-04-28 EP disclosed
EP-0930336-B1 Thermoplastic elastomers with good paintability, high resistance and elasticity and high impact resistant polymer blends prepared therefrom BOREALIS GMBH (AT) 2003-10-15 EP disclosed
EP-0884355-B1 Polyolefin foams with fine cells BOREALIS GMBH (AT) 2002-07-17 EP disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed
EP-0930336-A1 Thermoplastic elastomers with good paintability, high resistance and elasticity and high impact resistant polymer blends prepared therefrom Borealis AG (AT) 1999-07-21 EP disclosed
EP-0915134-A2 Thermoplastic elastomer with high resistance, elasticity and good paintability and high impact resistant polymer blends prepared therefrom Borealis AG (AT) 1999-05-12 EP disclosed
EP-0891989-A1 Modified polymers containing methylene groups PCD Polymere AG (AT) 1999-01-20 EP disclosed
EP-0884355-A1 Polyolefin foams with fine cells PCD Polymere AG (AT) 1998-12-16 EP disclosed
EP-0780400-B1 Partially hydrogenated aminotelechelic oligomers of 1,3-dienes and processes for preparing the same ATOCHEM ELF SA (FR) 1998-06-24 EP disclosed
US-5760157-A SELECTIVE HYDROGENATION OF NITRILE GROUPS USING A RANEY COBALT CATALYST ELF ATOCHEM, S.A. (FR) 1998-06-02 US disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0780400-A2 Partially hydrogenated aminotelechelic oligomers of 1,3-dienes and processes for preparing the same ELF ATOCHEM S.A. (FR) 1997-06-25 EP disclosed