Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 8/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 5/20 | 0.36 |
| ▸ | CTSB | P07858 | 5/20 | 0.36 |
| ▸ | CTSH | P09668 | 3/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21211687 | 1.00 | KDM4E (0.38) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL27452661 | 0.87 | — | — | |
| SCHEMBL15045504 | 0.79 | METAP1 (0.33) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL7418539 | 0.79 | METAP1 (0.37) | CTSKMETAP1 | |
| SCHEMBL7451839 | 0.79 | METAP1 (0.33) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL3504941 | 0.79 | METAP1 (0.37) | CTSKMETAP1 | |
| SCHEMBL1449256 | 0.79 | METAP1 (0.37) | CTSKMETAP1 | |
| SCHEMBL29278682 | 0.78 | CTSK (0.39) | CTSKCTSLCTSBCTSH | |
| SCHEMBL27437240 | 0.78 | CTSK (0.39) | CTSKCTSLCTSBCTSH | |
| SCHEMBL16433676 | 0.77 | CTSL (0.31) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101020641-A | Process for preparing amines by conditioning the catalyst with ammonia | DEGUSSA (DE) | 2007-08-22 | — | — | CN | claimed |
| CN-1230417-C | Process for preparing primary and secondary amines from nitriles | BASF AG (DE) | 2005-12-07 | — | — | CN | disclosed |
| CN-1220673-C | Preparation method of secondary amine by using hydrocyanic ester | BASF AG (DE) | 2005-09-28 | — | — | CN | disclosed |
| CN-1367164-A | Preparation method of secondary amine by using hydrocyanic ester | BASF AG (DE) | 2002-09-04 | — | — | CN | disclosed |
| CN-1365965-A | Process for preparing primary and secondary amines from nitriles | BASF AG (DE) | 2002-08-28 | — | — | CN | disclosed |