SCHEMBL6576567

SCHEMBL6576567

ClN(Cl)c1nc(-c2ccccc2)nc(N(Cl)Cl)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
HTT P42858 1/20 0.47
ADORA2A P29274 3/20 0.46
ADORA1 P30542 3/20 0.46
ADORA3 P0DMS8 2/20 0.46
ADORA2B P29275 2/20 0.46
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MAPK1 P28482 1/20 0.44
NR1H4 Q96RI1 2/20 0.43
LMNA P02545 2/20 0.42
NTSR1 P30989 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6578751 0.83 MEN1 (0.42) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL14274943 0.77 MEN1 (0.55) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL12073499 0.76 L3MBTL1 (0.56) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL10304591 0.76 ALDH1A1 (0.55) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL371042 0.74 L3MBTL1 (0.74) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL7179860 0.74 L3MBTL1 (0.48) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL197197 0.72 MEN1 (0.42) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL10031637 0.72 ACP1 (0.57) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL4597287 0.72 L3MBTL1 (0.47) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL75848 0.72 L3MBTL1 (0.70) MEN1KMT2AHTTADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930303-B1 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECH CORP (US) 2004-02-04 EP claimed
EP-0565774-B1 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECH CORP (US) 2001-03-28 EP claimed
EP-0930303-A2 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1999-07-21 EP claimed
US-5571915-A Process for preparing amide derivatives from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1996-11-05 US claimed
US-5288865-A Process for preparing amide derivatives from haloaminotriazines and acid halides AMERICAN CYANAMID COMPANY (US) 1994-02-22 US claimed
EP-0565774-A2 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1993-10-20 EP claimed
EP-0933370-A1 Tris-(2,2,6,6-tetramethyl-piperid-4-yl-aminocarbonyl)melamine CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933371-A1 N-halo acid amides CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933369-A1 Tris-(omega-haloacyl)melamines CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0930303-A2 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1999-07-21 EP disclosed