Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17769816 | 0.89 | MAPT (0.56) | ALOX5MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL10507286 | 0.89 | ALOX5 (0.51) | ALOX5MAPTTDP1MAPK1PTGES | |
| SCHEMBL1142464 | 0.87 | CES1 (0.53) | ALOX5MAPTTDP1MAPK1ALDH1A1 | |
| SCHEMBL5708190 | 0.80 | SMN1; SMN2 (0.57) | ALOX5MAPTTDP1PTGESALDH1A1 | |
| SCHEMBL31504604 | 0.79 | NPC1 (0.52) | ALOX5MAPTTDP1MAPK1PTGES | |
| SCHEMBL28159387 | 0.78 | TSHR (0.57) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL18328175 | 0.78 | TSHR (0.57) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL213819 | 0.78 | TSHR (0.57) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL12246447 | 0.78 | ADRB2 (0.54) | ALOX5MAPTTDP1MAPK1ALDH1A1 | |
| SCHEMBL4732226 | 0.77 | NSD2 (0.56) | TDP1ALDH1A1LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254092-B1 | RESOLUTION OF DL-RACEMIC MIXTURES | DEGUSSA (DE) | 2004-01-21 | — | — | EP | claimed |
| US-6673942-B1 | PREFERENTIAL CRYSTALLIZATION, PHYSICAL SEPARATION | DEGUSSA AG (DE) | 2004-01-06 | — | — | US | claimed |
| EP-1254092-A1 | RESOLUTION OF DL-RACEMIC MIXTURES | Degussa AG (DE) | 2002-11-06 | — | — | EP | claimed |
| WO-2001058835-A1 | RESOLUTION OF DL-RACEMIC MIXTURES | DEGUSSA AG (DE) | 2001-08-16 | — | — | WO | claimed |
| EP-1254092-B1 | RESOLUTION OF DL-RACEMIC MIXTURES | DEGUSSA (DE) | 2004-01-21 | — | — | EP | disclosed |
| US-6673942-B1 | PREFERENTIAL CRYSTALLIZATION, PHYSICAL SEPARATION | DEGUSSA AG (DE) | 2004-01-06 | — | — | US | disclosed |
| EP-1254092-A1 | RESOLUTION OF DL-RACEMIC MIXTURES | Degussa AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058835-A1 | RESOLUTION OF DL-RACEMIC MIXTURES | DEGUSSA AG (DE) | 2001-08-16 | — | — | WO | disclosed |