Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8521348 | 1.00 | CYP1A1 (0.34) | CYP1A1CXCR5NAMPTKCNH2 | |
| Sulfuric Acid SCHEMBL1424850 | 0.99 | CYP1A1 (0.35) | CYP1A1CXCR5NAMPTKCNH2 | |
| SCHEMBL28054351 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL3262722 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL28054371 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL1878428 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL498621 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL7934680 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL27995364 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 | |
| SCHEMBL287633 | 0.91 | KCNH2 (0.37) | CYP1A1CXCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728822-B1 | Aqueous paint composition | ROHM & HAAS (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-0798350-B1 | Paint composition | ROHM & HAAS (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5705560-A | PAINTS, ANIONIC POLYMER | ROHM AND HAAS COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| EP-0798350-A1 | Paint composition | ROHM AND HAAS COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| EP-0728822-A2 | Aqueous paint composition | ROHM AND HAAS COMPANY (US) | 1996-08-28 | — | — | EP | disclosed |