Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579566 | 0.92 | TSHR (0.50) | TSHRMAPK10SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7980736 | 0.86 | RAB9A (0.47) | TSHRMAPK10SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6579573 | 0.82 | TSHR (0.48) | TSHRMAPK10SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6581134 | 0.82 | MAPT (0.49) | SMN1; SMN2RAB9ANPC1POLBMAPT | |
| SCHEMBL6581483 | 0.82 | TDP1 (0.46) | TSHRMAPK10SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6579783 | 0.76 | TSHR (0.48) | TSHRMAPK10SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6581961 | 0.75 | LMNA (0.44) | TSHRMAPK10SMN1; SMN2MAPTHPGD | |
| Ethyl Benzoate SCHEMBL27551058 | 0.74 | MAPT (0.40) | SMN1; SMN2RAB9ANPC1POLBMAPT | |
| SCHEMBL6576914 | 0.74 | TDP1 (0.44) | TSHRSMN1; SMN2NPC1POLBMAPT | |
| SCHEMBL6578873 | 0.72 | SMN1; SMN2 (0.49) | TSHRMAPK10SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |