SCHEMBL6576706

SCHEMBL6576706

O=C(Oc1ccccc1)N(c1ccccc1)c1ccccc1.c1ncncn1

nearest known ligand 0.82

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.82
ATM Q13315 1/20 0.82
TDP1 Q9NUW8 1/20 0.82
NPSR1 Q6W5P4 3/20 0.61
TSHR P16473 2/20 0.54
PTGES O14684 1/20 0.45
MAOB P27338 2/20 0.45
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
LIPE Q05469 1/20 0.43
CHRM4 P08173 1/20 0.41
CHRM3 P20309 1/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 2/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867886 0.91 L3MBTL1 (1.00) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL20336349 0.87 L3MBTL1 (0.92) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL2821898 0.81 ATM (0.69) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL21729903 0.79 L3MBTL1 (0.76) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL14830428 0.78 ATM (0.74) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL28489728 0.76 ATM (0.72) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL6763307 0.76 L3MBTL1 (0.71) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL16965604 0.75 L3MBTL1 (0.70) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL10871503 0.75 L3MBTL1 (0.70) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL31550469 0.74 L3MBTL1 (0.63) L3MBTL1ATMTDP1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930303-B1 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECH CORP (US) 2004-02-04 EP disclosed
EP-0933371-B1 N-halo acid amides CYTEC TECH CORP (US) 2003-04-09 EP disclosed
EP-0565774-B1 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECH CORP (US) 2001-03-28 EP disclosed
EP-0933371-A1 N-halo acid amides CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933369-A1 Tris-(omega-haloacyl)melamines CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933370-A1 Tris-(2,2,6,6-tetramethyl-piperid-4-yl-aminocarbonyl)melamine CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0930303-A2 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1999-07-21 EP disclosed
US-5571915-A Process for preparing amide derivatives from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1996-11-05 US disclosed
US-5405959-A Haloaminotraizines and acid halides CYTEC TECHNOLOGY CORP. (US) 1995-04-11 US disclosed
US-5288865-A Process for preparing amide derivatives from haloaminotriazines and acid halides AMERICAN CYANAMID COMPANY (US) 1994-02-22 US disclosed
EP-0565774-A2 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1993-10-20 EP disclosed
EP-0541966-A2 Process for preparing amide derivatives from halomines and acid halides AMERICAN CYANAMID COMPANY (US) 1993-05-19 EP disclosed