Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | MME | P08473 | 5/20 | 0.54 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | CPA1 | P15085 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.51 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600694 | 0.90 | ALDH1A1 (0.60) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL17761604 | 0.90 | ALDH1A1 (0.60) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL517463 | 0.90 | ALDH1A1 (0.60) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL9995407 | 0.88 | ALDH1A1 (0.59) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL8522871 | 0.85 | MME (0.50) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL20583645 | 0.85 | MME (0.50) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL20583647 | 0.85 | MME (0.50) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL20583644 | 0.85 | MME (0.50) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL15478876 | 0.84 | MME (0.57) | HDAC1HDAC6MMEACE | |
| SCHEMBL12406884 | 0.83 | CYP17A1 (0.44) | HDAC1HDAC6MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774036-B2 | Process for early sacubitril intermediates | NOVARTIS AG (CH) | 2020-09-15 | — | — | US | disclosed |
| EP-1397358-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002102801-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774036-B2 | Process for early sacubitril intermediates | MME, ACE, DNPEP | ALDH1A1 247/4885THRB 1107/4885CYP2C9 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.