Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9995407

COC(=O)C(C)Cc1ccccc1.N

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
THRB P10828 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CYP3A4 P08684 3/20 0.54
TSHR P16473 1/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
MAPK1 P28482 1/20 0.53
ATM Q13315 1/20 0.53
HPGD P15428 1/20 0.51
MAPT P10636 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CA12 O43570 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17761604 0.98 ALDH1A1 (0.60) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL517463 0.98 ALDH1A1 (0.60) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL2600694 0.98 ALDH1A1 (0.60) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL6576829 0.88 ALDH1A1 (0.55) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL27977003 0.85 LTA4H (0.68) NPC1RAB9AL3MBTL1LMNA
SCHEMBL21366441 0.85 LTA4H (0.68) NPC1RAB9AL3MBTL1LMNA
SCHEMBL13386048 0.84 ALDH1A1 (0.55) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL18300625 0.84 HSD17B10 (0.50) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL4591527 0.82 ACACB (0.49) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL1531741 0.82 ALDH1A1 (0.52) ALDH1A1THRBCYP2C9CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2798010-A1 MULTI-COMPONENT TYPE CURABLE SILICONE RUBBER COMPOSITION, MATERIAL FOR ELECTRONIC PARTS USING SUCH, AND SOLAR CELL MODULE Dow Corning Toray Co., Ltd. (JP) 2014-11-05 EP disclosed
US-20140238471-A1 Multi-Component Type Curable Silicone Rubber Composition, Material For Electronic Parts Using Such, And Solar Cell Module DOW CORNING TORAY CO LTD (JP) 2014-08-28 US disclosed
WO-2013100175-A1 MULTI-COMPONENT TYPE CURABLE SILICONE RUBBER COMPOSITION, MATERIAL FOR ELECTRONIC PARTS USING SUCH, AND SOLAR CELL MODULE DOW CORNING TORAY CO., LTD. (JP) 2013-07-04 WO disclosed
WO-2011161690-A1 PROCESSES FOR THE PREPARATION OF (+)-N,N-DIMETHYL-2-[1-(NAPHTHALENYLOXY) ETHYL] BENZENE METHANAMINE AND INTERMEDIATES THEREOF SYMED LABS LIMITED (IN) 2011-12-29 WO disclosed