Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980686 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL7976008 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL6582186 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL7978004 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10PTPN11 | |
| SCHEMBL6579485 | 0.83 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL27473235 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL7999095 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6580951 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL6580954 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL27387414 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |