Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579041 | 0.86 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL6576831 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10HPGDGSK3B | |
| SCHEMBL7974970 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL7999095 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10HPGDGSK3B | |
| SCHEMBL7980686 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL27389334 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL27387414 | 0.80 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10HPGDGSK3B | |
| SCHEMBL7978073 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL27491020 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL8004161 | 0.76 | TTR (0.47) | KDM4EALDH1A1HSD17B10HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1185245-C | Quinolinone glucoside, its preparing method and antitransformation reaction agent | DANIPPON INKA ND CHEMICALS INC (JP) | 2005-01-19 | — | — | CN | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| CN-1228436-A | Quinolinone glucoside, its preparing method and antitransformation reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-09-15 | — | — | CN | disclosed |