Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576747 | 0.87 | ADORA3 (0.54) | ADORA3ADORA1LMNAALDH1A1GLA | |
| SCHEMBL6576827 | 0.87 | ADORA3 (0.53) | ADORA3ADORA1LMNAALDH1A1GLA | |
| SCHEMBL6574123 | 0.86 | ADORA3 (0.51) | ADORA3ADORA1LMNAALDH1A1GLA | |
| SCHEMBL6575053 | 0.83 | ADORA3 (0.64) | ADORA3ADORA1LMNAALDH1A1GLA | |
| SCHEMBL6576750 | 0.81 | DOT1L (0.48) | ADORA3ADORA1ALDH1A1PMP22NPC1 | |
| SCHEMBL6572956 | 0.81 | ADORA3 (0.58) | ADORA3ADORA1PMP22SMN1; SMN2HTT | |
| SCHEMBL6576646 | 0.79 | ADORA3 (0.50) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574553 | 0.79 | ADORA3 (0.60) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574608 | 0.78 | ADORA3 (0.59) | ADORA3ADORA1PMP22SMN1; SMN2HTT | |
| SCHEMBL6257355 | 0.77 | ADORA1 (0.59) | ADORA3ADORA1LMNAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |