Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576646 | 0.89 | ADORA3 (0.50) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6572956 | 0.86 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BTP53TSHR | |
| SCHEMBL6575094 | 0.85 | ADORA3 (0.49) | DOT1LADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL6574553 | 0.84 | ADORA3 (0.60) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6574608 | 0.84 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BTP53TSHR | |
| SCHEMBL6575273 | 0.82 | ADORA3 (0.51) | ADORA3ADORA2AADORA2BTP53TSHR | |
| SCHEMBL6576848 | 0.81 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BTSHRNFKB1 | |
| SCHEMBL6576747 | 0.81 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BTSHRNFKB1 | |
| SCHEMBL6575274 | 0.81 | ADORA2A (0.51) | ADORA3ADORA2AADORA2BTP53TSHR | |
| SCHEMBL6574563 | 0.81 | ADORA3 (0.47) | ADORA3ADORA2AADORA2BTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |