Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 15/20 | 0.82 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119505 | 0.99 | NR1H4 (0.83) | NR1H4CYSLTR1MEN1NPC1KMT2A | |
| SCHEMBL6165569 | 0.99 | NR1H4 (0.83) | NR1H4CYSLTR1MEN1NPC1KMT2A | |
| SCHEMBL8108301 | 0.96 | NR1H4 (0.78) | NR1H4MEN1NPC1KMT2APOLB | |
| SCHEMBL6581896 | 0.92 | NR1H4 (0.72) | NR1H4MEN1NPC1KMT2APOLB | |
| SCHEMBL6577998 | 0.89 | NR1H4 (0.65) | NR1H4MEN1KMT2APOLBRAB9A | |
| SCHEMBL6577802 | 0.86 | NR1H4 (0.62) | NR1H4MEN1KMT2APOLBRAB9A | |
| SCHEMBL6577743 | 0.85 | NR1H4 (0.80) | NR1H4MEN1NPC1KMT2APOLB | |
| SCHEMBL7476886 | 0.85 | NR1H4 (0.66) | NR1H4CYSLTR1MEN1NPC1KMT2A | |
| SCHEMBL6577705 | 0.84 | NR1H4 (0.78) | NR1H4MEN1NPC1KMT2ARAB9A | |
| SCHEMBL8827735 | 0.83 | NR1H4 (0.59) | NR1H4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |