Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903057 | 0.77 | — | — | |
| SCHEMBL1116709 | 0.76 | CPA1 (0.55) | CPA1ALDH1A1KDM4EMAPT | |
| SCHEMBL11875036 | 0.74 | CPA1 (0.44) | CPA1ALDH1A1 | |
| SCHEMBL11806368 | 0.74 | — | — | |
| SCHEMBL5467078 | 0.74 | ALDH1A1 (0.41) | CPA1ALDH1A1KDM4EMAPT | |
| SCHEMBL12323796 | 0.73 | TSHR (0.33) | CPA1ALDH1A1 | |
| SCHEMBL27888164 | 0.73 | TSHR (0.33) | CPA1ALDH1A1 | |
| SCHEMBL7166034 | 0.73 | CPA1 (0.37) | CPA1 | |
| SCHEMBL17176858 | 0.73 | — | — | |
| Nitric Acid SCHEMBL8587449 | 0.72 | CPA1 (0.52) | CPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140826-B1 | METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR | ABBOTT GMBH & CO KG (DE) | 2004-05-06 | — | — | EP | disclosed |
| US-6559318-B1 | Hydrolysis of 1,1,3,3-tetraalkoxyalkane to 3,3-dialkoxypropionaldehyde using acid catalyst; Henry reaction with nitromethane; dehydration, Diels-Alder reaction, hydrogenation, cyanation, saponification | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-06 | — | — | US | disclosed |
| CN-1334803-A | Process for the preparation of (2S,4R,9S) -octahydro-1H-indole-2-carboxylic acid and intermediates thereof | BASF AG (DE) | 2002-02-06 | — | — | CN | disclosed |
| EP-1140826-A1 | METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040555-A1 | METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-13 | — | — | WO | disclosed |