Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503616 | 0.79 | SLC6A2 (0.45) | CYP2D6SLC6A2SLC6A4NOS2KCNH2 | |
| SCHEMBL7650957 | 0.76 | SLC6A2 (0.42) | CYP2D6SLC6A2SLC6A4NOS2KCNH2 | |
| SCHEMBL30386539 | 0.76 | PRMT5 (0.47) | CTSLIDO1AAK1MEN1GAA | |
| SCHEMBL17674434 | 0.73 | IDO1 (0.48) | CTSLIDO1AAK1MEN1GAA | |
| SCHEMBL7414731 | 0.72 | PTGDR2 (0.45) | IDO1GAAPTGDR2 | |
| SCHEMBL7644451 | 0.72 | NOS2 (0.58) | CYP2D6SLC6A2SLC6A4NOS2KCNH2 | |
| SCHEMBL6337819 | 0.72 | NOS2 (0.67) | CYP2D6SLC6A2SLC6A4NOS2KCNH2 | |
| SCHEMBL25345326 | 0.70 | CTSL (0.53) | CTSL | |
| SCHEMBL25345323 | 0.70 | CTSL (0.53) | CTSL | |
| SCHEMBL30597398 | 0.70 | NOS2 (0.43) | NOS2CTSLIDO1AAK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263715-B1 | NOVEL PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-04-28 | — | — | EP | disclosed |