Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579280 | 0.87 | CYP1A2 (0.37) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL6579337 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL6578826 | 0.85 | CYP1A2 (0.39) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL6579894 | 0.85 | ALDH1A1 (0.40) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL6577138 | 0.85 | MAOA (0.36) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL6579381 | 0.84 | ALDH1A1 (0.35) | HSD17B10LMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL6579376 | 0.84 | ALDH1A1 (0.35) | HSD17B10LMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL6577077 | 0.83 | SMN1; SMN2 (0.41) | LMNAALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL6576926 | 0.81 | CYP1A2 (0.38) | MAOACHRM2CHRM3HTR2CCHRNA4 | |
| SCHEMBL6579643 | 0.81 | CYP1A2 (0.41) | MAOACHRM2CHRM3HTR2CCHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |