Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.39 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.39 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.39 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.39 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.39 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.39 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.39 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.39 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.39 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.39 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.39 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.39 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.39 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579055 | 1.00 | ALOX15 (0.48) | ALOX15MGAMGAASIPTPN1 | |
| SCHEMBL7977894 | 0.80 | VKORC1 (0.36) | ALOX15TDP1 | |
| SCHEMBL7977898 | 0.80 | VKORC1 (0.36) | ALOX15TDP1 | |
| SCHEMBL7988449 | 0.76 | TDP1 (0.44) | ALOX15MGAMGAASIPTPN1 | |
| SCHEMBL7988453 | 0.76 | TDP1 (0.44) | ALOX15MGAMGAASIPTPN1 | |
| SCHEMBL6581127 | 0.74 | KDM4E (0.43) | GAA | |
| SCHEMBL8494511 | 0.74 | ALOX15 (0.62) | ALOX15MGAMGAASIPTPN1 | |
| SCHEMBL8494952 | 0.72 | ALOX15 (0.60) | ALOX15MGAMGAASIPTPN1 | |
| SCHEMBL8494944 | 0.72 | ALOX15 (0.60) | ALOX15MGAMGAASIPTPN1 | |
| SCHEMBL8002130 | 0.72 | TDP1 (0.44) | ALOX15MGAMGAASIPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |