Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977898 | 1.00 | VKORC1 (0.36) | VKORC1ALOX15PSEN1ACHEGSK3B | |
| SCHEMBL6577089 | 0.80 | PSEN1 (0.42) | VKORC1ALOX15PSEN1ACHEGSK3B | |
| SCHEMBL6577085 | 0.80 | PSEN1 (0.42) | VKORC1ALOX15PSEN1ACHEGSK3B | |
| SCHEMBL6579055 | 0.80 | ALOX15 (0.48) | ALOX15TDP1 | |
| SCHEMBL6579061 | 0.80 | ALOX15 (0.48) | ALOX15TDP1 | |
| SCHEMBL6579041 | 0.74 | ALDH1A1 (0.40) | MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8831034 | 0.69 | ALOX15 (0.34) | ALOX15MAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL8831038 | 0.69 | ALOX15 (0.34) | ALOX15MAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL6579311 | 0.68 | ALOX15 (0.44) | VKORC1ALOX15MAPTMAPK1ALDH1A1 | |
| SCHEMBL6579305 | 0.68 | ALOX15 (0.44) | VKORC1ALOX15MAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |