Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579842 | 0.88 | MEN1 (0.45) | THRATHRBALDH1A1KDM4ETSHR | |
| SCHEMBL6582006 | 0.87 | CA12 (0.48) | ALDH1A1KDM4ETSHRLMNACA12 | |
| SCHEMBL6578896 | 0.86 | ALDH1A1 (0.41) | THRATHRBALDH1A1KDM4EHPGD | |
| SCHEMBL6579314 | 0.86 | ALDH1A1 (0.44) | THRATHRBALDH1A1KDM4ETSHR | |
| SCHEMBL6582373 | 0.86 | ALDH1A1 (0.41) | THRATHRBALDH1A1KDM4EHPGD | |
| SCHEMBL6582955 | 0.86 | ALDH1A1 (0.44) | THRATHRBALDH1A1KDM4ETSHR | |
| SCHEMBL6579475 | 0.84 | LMNA (0.41) | THRATHRBALDH1A1KDM4EHPGD | |
| SCHEMBL6582112 | 0.84 | LMNA (0.41) | THRATHRBALDH1A1KDM4EHPGD | |
| SCHEMBL6579935 | 0.84 | LMNA (0.41) | THRATHRBALDH1A1KDM4EHPGD | |
| SCHEMBL6579455 | 0.83 | MEN1 (0.41) | ALDH1A1KDM4EHPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |