⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170809 | 0.91 | — | — | |
| SCHEMBL10667761 | 0.88 | FAAH (0.39) | — | |
| SCHEMBL7765709 | 0.88 | — | — | |
| SCHEMBL7771403 | 0.88 | FAAH (0.39) | — | |
| SCHEMBL2882276 | 0.80 | — | — | |
| SCHEMBL4740198 | 0.76 | TSHR (0.47) | — | |
| SCHEMBL6725573 | 0.75 | — | — | |
| SCHEMBL1685807 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL8774964 | 0.73 | APEX1 (0.36) | — | |
| SCHEMBL6706926 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635498-B1 | Quinazoline derivatives and their use as anti-cancer agents | SYNGENTA LTD (GB) | 2001-04-18 | — | — | EP | claimed |
| US-5475001-A | Quinazoline derivatives | ZENECA LIMITED (GB) | 1995-12-12 | — | — | US | claimed |
| WO-1995003283-A1 | QUINAZOLINE DERIVATIVES AND THEIR USE AS ANTI-CANCER AGENTS | ZENECA LIMITED (GB) | 1995-02-02 | — | — | WO | claimed |
| EP-0635498-A1 | Quinazoline derivatives and their use as anti-cancer agents | ZENECA LIMITED (GB) | 1995-01-25 | — | — | EP | claimed |
| EP-0930303-B1 | A process for preparing isocyanate compounds from haloaminotriazines and acid halides | CYTEC TECH CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-0933371-B1 | N-halo acid amides | CYTEC TECH CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0635498-B1 | Quinazoline derivatives and their use as anti-cancer agents | SYNGENTA LTD (GB) | 2001-04-18 | — | — | EP | disclosed |
| EP-0565774-B1 | Process for preparing amide derivatives from halominotriazines and acid halides | CYTEC TECH CORP (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| EP-0933370-A1 | Tris-(2,2,6,6-tetramethyl-piperid-4-yl-aminocarbonyl)melamine | CYTEC TECHNOLOGY CORP. (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933371-A1 | N-halo acid amides | CYTEC TECHNOLOGY CORP. (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933369-A1 | Tris-(omega-haloacyl)melamines | CYTEC TECHNOLOGY CORP. (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4897105-A | (1,2,4)-THIADIAZOLO(2,3-A)PYRIMIDINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0239064-A2 | Herbicidal compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |
| US-4056544-A | Anthraquinone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |