Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 8/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280815 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1GAACNR2HPGD | |
| SCHEMBL6576521 | 0.91 | KDM4E (0.47) | KDM4EALDH1A1GAACNR2EGFR | |
| SCHEMBL6582560 | 0.87 | ALDH1A1 (0.46) | KDM4EALDH1A1GAACNR2HPGD | |
| SCHEMBL6581314 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1GAACNR2HIF1A | |
| SCHEMBL6277841 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1GAACNR2HIF1A | |
| SCHEMBL6277838 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1GAACNR2HIF1A | |
| SCHEMBL6581007 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1GAACNR2HPGD | |
| SCHEMBL8004161 | 0.85 | TTR (0.47) | KDM4EALDH1A1CNR2HPGDHSD17B10 | |
| SCHEMBL6579500 | 0.85 | TTR (0.47) | KDM4EALDH1A1CNR2HPGDHSD17B10 | |
| SCHEMBL8004925 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1GAACNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |