Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362298 | 0.82 | TTR (0.47) | ATMPOLBMAPTKMT2AALDH1A1 | |
| SCHEMBL28917715 | 0.82 | NPC1 (0.50) | POLBMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30279760 | 0.82 | NPC1 (0.50) | POLBMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8950654 | 0.80 | KMT2A (0.49) | POLBKMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL557799 | 0.78 | ATM (1.00) | ATMPOLBMAPTKMT2AALDH1A1 | |
| SCHEMBL30230461 | 0.78 | ATM (1.00) | ATMPOLBMAPTKMT2AALDH1A1 | |
| SCHEMBL8635081 | 0.78 | ATM (1.00) | ATMPOLBMAPTKMT2AALDH1A1 | |
| SCHEMBL6581703 | 0.78 | CA5A (0.52) | KMT2AALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL13250642 | 0.77 | POLB (0.73) | ATMPOLBMAPTKMT2AALDH1A1 | |
| SCHEMBL25612190 | 0.77 | CA12 (0.50) | MAPTKMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737680-B1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0737680-A1 | (Phenylalkylaminoalkyloxyl)-hetero-aryl compounds, processes and intermediates for their preparation and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1996-10-16 | — | — | EP | disclosed |
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |