Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581703 | 0.87 | CA5A (0.52) | KMT2AL3MBTL1GAAHSD17B10NPSR1 | |
| SCHEMBL8950532 | 0.83 | DRD2 (0.47) | KMT2AL3MBTL1GAAHSD17B10MEN1 | |
| SCHEMBL30279760 | 0.81 | NPC1 (0.50) | KMT2AGAAMEN1LMNASMN1; SMN2 | |
| SCHEMBL28917715 | 0.81 | NPC1 (0.50) | KMT2AGAAMEN1LMNASMN1; SMN2 | |
| SCHEMBL6579408 | 0.80 | ATM (0.61) | KMT2AL3MBTL1LMNASMN1; SMN2POLB | |
| SCHEMBL2403269 | 0.79 | KMT2A (0.71) | KMT2AL3MBTL1GAACYP2C19LMNA | |
| SCHEMBL3362298 | 0.79 | TTR (0.47) | KMT2AL3MBTL1NPSR1MEN1CYP2C19 | |
| SCHEMBL4857081 | 0.76 | ALDH1A1 (0.46) | KMT2AGAAMEN1CYP1A2CYP2C19 | |
| SCHEMBL8838328 | 0.76 | NPC1 (0.43) | KMT2ANPSR1MEN1POLBTSHR | |
| SCHEMBL8838307 | 0.75 | KMT2A (0.42) | KMT2AL3MBTL1GAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |