SCHEMBL6579460

SCHEMBL6579460

CCOC(=O)c1ccccc1OC(=O)c1ccccc1C(=O)Oc1ccccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
PTK2B Q14289 1/20 0.54
NPSR1 Q6W5P4 3/20 0.51
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 2/20 0.50
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
MAPT P10636 5/20 0.47
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47
CDC25B P30305 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
METTL3 Q86U44 1/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706131 0.97 TSHR (0.66) TSHRPTK2BNPSR1ALDH1A1HSD17B10
SCHEMBL5706101 0.94 TSHR (0.54) TSHRPTK2BNPSR1ALDH1A1HSD17B10
SCHEMBL5706049 0.91 TSHR (0.57) TSHRPTK2BNPSR1ALDH1A1HSD17B10
SCHEMBL8500487 0.86 KDM4E (0.53) TSHRPTK2BNPSR1ALDH1A1HSD17B10
SCHEMBL5706005 0.85 TSHR (0.66) TSHRNPSR1ALDH1A1HSD17B10LMNA
SCHEMBL5706110 0.85 TSHR (0.66) TSHRNPSR1ALDH1A1HSD17B10LMNA
SCHEMBL6579462 0.85 TSHR (0.57) TSHRNPSR1ALDH1A1HSD17B10LMNA
SCHEMBL5706067 0.84 TSHR (0.65) TSHRPTK2BNPSR1ALDH1A1HSD17B10
SCHEMBL10602875 0.84 PTK2B (0.70) PTK2BNPSR1ALDH1A1HSD17B10LMNA
SCHEMBL5706098 0.83 SLC6A3 (0.64) TSHRPTK2BNPSR1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed