Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HLCS | P50747 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803047 | 0.87 | HLCS (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1271190 | 0.85 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2536441 | 0.85 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| Hydrochloric Acid SCHEMBL3417755 | 0.84 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2596553 | 0.83 | TDP1 (0.59) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1309033 | 0.82 | TDP1 (0.57) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2350071 | 0.82 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| Aminocaproic Acid SCHEMBL1518517 | 0.81 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL12990072 | 0.81 | HLCS (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL16141167 | 0.81 | HLCS (0.72) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821696-B1 | PEPTIDE ANTAGONISTS OF CELLULAR MITOGENESIS AND MOTOGENESIS AND THEIR THERAPEUTIC USE | PHARMACIA ITALIA SPA (IT) | 2004-05-06 | — | — | EP | disclosed |
| US-6288037-B1 | C-TERMINALLY MODIFIED PENTAPEPTIDES CONTAINING VALINE AND ASPARTIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6245742-B1 | ANTITUMOR, ANTICARCINOGENIC AND ANTIMETASTASIS AGENTS; VIRICIDES, PSORIASIS, ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, PSORIASIS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-06-12 | — | — | US | disclosed |
| EP-0880542-A2 | SUBSTRATES AND INHIBITORS FOR CYSTEINE PROTEASE ICH-1 | BASF AG (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0821696-A1 | PEPTIDE ANTAGONISTS OF CELLULAR MITOGENESIS AND MOTOGENESIS AND THEIR THERAPEUTIC USE | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-02-04 | — | — | EP | disclosed |
| WO-1997030079-A1 | PEPTIDE ANTAGONISTS OF CELLULAR MITOGENESIS AND MOTOGENESIS AND THEIR THERAPEUTIC USE | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-08-21 | — | — | WO | disclosed |
| WO-1997027220-A2 | SUBSTRATES AND INHIBITORS FOR CYSTEINE PROTEASE ICH-1 | BASF AG (US) | 1997-07-31 | — | — | WO | disclosed |