Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579658 | 0.87 | TDP1 (0.59) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL15020036 | 0.85 | HLCS (0.65) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL7122397 | 0.83 | TDP1 (0.61) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL2479213 | 0.83 | HLCS (0.73) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL24474061 | 0.81 | HLCS (0.67) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL25724512 | 0.81 | HLCS (0.66) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL9841668 | 0.81 | HLCS (0.65) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21549581 | 0.80 | HLCS (0.64) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL17830117 | 0.79 | HLCS (0.82) | HLCSTDP1MEN1ABL1LMNA | |
| Biotin SCHEMBL6033491 | 0.79 | TDP1 (0.87) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063624-A1 | Method of inhibiting the transition of free HIV virus through the cllular mucosal barrier | KAGE ANDREAS (DE) | 2004-04-01 | — | — | US | disclosed |