Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579782 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1GAATYRHPGD | |
| SCHEMBL7975938 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDKDM1A | |
| SCHEMBL7978025 | 0.74 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAHPGDTP53 | |
| SCHEMBL5741498 | 0.74 | KDM4E (0.74) | KDM4EALDH1A1GAAHPGDKDM1A | |
| SCHEMBL15219792 | 0.73 | CNR2 (0.44) | KDM4EALDH1A1TYRHPGDCNR2 | |
| SCHEMBL6579613 | 0.72 | ALDH1A1 (0.51) | KDM4EALDH1A1GAAHPGDKDM1A | |
| SCHEMBL7980793 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDKDM1A | |
| SCHEMBL6576851 | 0.70 | TUBB4A (0.42) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL6577102 | 0.70 | KDM4E (0.47) | KDM4EALDH1A1HPGDCNR2MAPT | |
| SCHEMBL6578821 | 0.70 | TTR (0.49) | KDM4EALDH1A1GAAHPGDKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |