Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787984 | 0.83 | PDE4A (0.43) | NR1H4 | |
| SCHEMBL15981207 | 0.80 | PPARA (0.68) | NR1H4PPARAPLA2G4BPPARGFFAR1 | |
| SCHEMBL5049112 | 0.80 | PPARG (0.71) | NR1H4PPARAPLA2G4BPPARGFFAR1 | |
| SCHEMBL6579956 | 0.79 | LMNA (0.58) | GAALMNAMAPK1L3MBTL1 | |
| SCHEMBL27613074 | 0.78 | FFAR1 (0.69) | NR1H4PPARAPLA2G4BPPARGFFAR1 | |
| SCHEMBL11485988 | 0.75 | PPARA (0.83) | PPARAPPARGGAALMNAMAPK1 | |
| SCHEMBL6060917 | 0.75 | PARP10 (0.71) | NR1H4PLA2G4BFFAR1S1PR1S1PR3 | |
| SCHEMBL7502356 | 0.75 | PLA2G4B (0.66) | NR1H4PPARAPLA2G4BFFAR1S1PR1 | |
| SCHEMBL2312866 | 0.74 | PLA2G4B (0.83) | NR1H4PLA2G4BFFAR1S1PR1SRD5A2 | |
| SCHEMBL2127003 | 0.74 | PPARA (0.81) | PPARAGAALMNAMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |