Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579851 | 1.00 | TRPV1 (0.36) | TRPV1ICMTCSNK1DALDH1A1RAB9A | |
| SCHEMBL6577136 | 0.94 | EGFR (0.32) | TRPV1 | |
| SCHEMBL6577141 | 0.94 | EGFR (0.32) | TRPV1 | |
| SCHEMBL6582338 | 0.83 | MEN1 (0.35) | TRPV1LMNATP53HSD17B10 | |
| SCHEMBL6582345 | 0.83 | MEN1 (0.35) | TRPV1LMNATP53HSD17B10 | |
| SCHEMBL27492420 | 0.82 | ALDH1A1 (0.35) | TRPV1ICMTALDH1A1LMNAKDM4E | |
| SCHEMBL6579803 | 0.77 | ALDH1A1 (0.40) | CSNK1DALDH1A1RAB9ALMNATP53 | |
| SCHEMBL6582265 | 0.77 | TRPV1 (0.35) | TRPV1 | |
| SCHEMBL6582259 | 0.77 | TRPV1 (0.35) | TRPV1 | |
| SCHEMBL6582084 | 0.77 | MEN1 (0.39) | ALDH1A1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |