Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582338 | 1.00 | MEN1 (0.35) | MEN1LMNATP53KMT2AHSD17B10 | |
| SCHEMBL6577136 | 0.87 | EGFR (0.32) | EGFRTRPV1ACHE | |
| SCHEMBL6577141 | 0.87 | EGFR (0.32) | EGFRTRPV1ACHE | |
| SCHEMBL6579851 | 0.83 | TRPV1 (0.36) | LMNATP53HSD17B10TRPV1 | |
| SCHEMBL6579860 | 0.83 | TRPV1 (0.36) | LMNATP53HSD17B10TRPV1 | |
| SCHEMBL27523579 | 0.80 | CTSL (0.34) | MEN1LMNAKMT2ATRPV1MAOB | |
| SCHEMBL6582265 | 0.77 | TRPV1 (0.35) | TRPV1MAOBMAOA | |
| SCHEMBL6582259 | 0.77 | TRPV1 (0.35) | TRPV1MAOBMAOA | |
| SCHEMBL6581436 | 0.76 | LMNA (0.44) | MEN1LMNATP53KMT2AHSD17B10 | |
| SCHEMBL6582042 | 0.76 | KMT2A (0.38) | KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |