Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579568 | 0.87 | P2RX4 (0.50) | P2RX4ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20154173 | 0.82 | ALDH1A1 (0.47) | P2RX4P2RX1P2RX3ALDH1A1KMT2A | |
| SCHEMBL24704613 | 0.79 | ATM (0.46) | P2RX4P2RX1P2RX3ALDH1A1KMT2A | |
| SCHEMBL5662395 | 0.78 | DAGLA (0.49) | P2RX4P2RX1P2RX3ALDH1A1KMT2A | |
| SCHEMBL6582834 | 0.78 | MAPK1 (0.44) | ALDH1A1NPSR1CYP2C19CYP2C9NPC1 | |
| SCHEMBL14822692 | 0.73 | TDP1 (0.50) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL20154211 | 0.73 | ALDH1A1 (0.47) | P2RX4P2RX1P2RX3ALDH1A1KMT2A | |
| SCHEMBL2495018 | 0.73 | GAA (0.55) | P2RX4P2RX1P2RX3KMT2ANPSR1 | |
| SCHEMBL20223317 | 0.71 | KDM4C (0.56) | ALDH1A1KMT2AMEN1CYP2C19CYP1A2 | |
| SCHEMBL16249204 | 0.71 | TDP1 (0.47) | ALDH1A1KMT2ACYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |