Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579876 | 0.82 | P2RX4 (0.47) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL24704613 | 0.82 | ATM (0.46) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL20154211 | 0.79 | ALDH1A1 (0.47) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL5662395 | 0.78 | DAGLA (0.49) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL20154212 | 0.76 | TDP1 (0.50) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL21187189 | 0.75 | P2RX4 (0.43) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL9880597 | 0.75 | ALDH1A1 (0.49) | ALDH1A1P2RX4P2RX1P2RX3HTR2C | |
| SCHEMBL22825569 | 0.73 | L3MBTL1 (0.57) | ALDH1A1LMNASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2495018 | 0.73 | GAA (0.55) | P2RX4P2RX1P2RX3LMNAKMT2A | |
| SCHEMBL20419496 | 0.73 | ALDH1A1 (0.47) | ALDH1A1P2RX4P2RX1P2RX3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538512-B1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-06-16 | — | — | EP | disclosed |
| WO-2021018839-A1 | ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2021-02-04 | — | — | WO | disclosed |
| WO-2019002132-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018087036-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2018-05-17 | — | — | WO | disclosed |