Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.67 |
| ▸ | PLK1 | P53350 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MDH1 | P40925 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577998 | 0.89 | NR1H4 (0.65) | TRPV1PLK1NR1H4RAB9AMEN1 | |
| SCHEMBL6577802 | 0.89 | NR1H4 (0.62) | TRPV1NR1H4RAB9AMEN1KMT2A | |
| SCHEMBL7824191 | 0.87 | TRPV1 (0.75) | TRPV1PLK1NR1H4KDM4EMEN1 | |
| SCHEMBL6580260 | 0.87 | TRPV1 (0.56) | TRPV1NR1H4NPC1RAB9AMEN1 | |
| SCHEMBL6577705 | 0.84 | NR1H4 (0.78) | NR1H4KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL6580248 | 0.81 | NR1H4 (0.57) | NR1H4NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL6580464 | 0.81 | NR1H4 (0.58) | NR1H4NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL6346822 | 0.81 | KCNK3 (0.71) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8108301 | 0.80 | NR1H4 (0.78) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8119505 | 0.79 | NR1H4 (0.83) | NR1H4NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |