Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580464 | 0.93 | NR1H4 (0.58) | NR1H4KCNK3KMT2AMEN1KCNK9 | |
| SCHEMBL6346822 | 0.88 | KCNK3 (0.71) | KCNK3KMT2AMEN1KCNK9POLB | |
| SCHEMBL6580479 | 0.87 | NR1H4 (0.80) | NR1H4KMT2AMEN1RXFP1POLB | |
| SCHEMBL6580260 | 0.86 | TRPV1 (0.56) | NR1H4KCNK3KMT2AMEN1KCNK9 | |
| SCHEMBL6580034 | 0.85 | KCNK9 (0.72) | KCNK3KMT2AMEN1KCNK9RXFP1 | |
| SCHEMBL23513412 | 0.84 | NPC1 (0.74) | KCNK3KMT2AMEN1KCNK9KCNH2 | |
| SCHEMBL12228168 | 0.84 | RAB9A (0.71) | KCNK3KMT2AMEN1KCNK9KCNH2 | |
| SCHEMBL2076281 | 0.83 | HPSE (0.72) | NR1H4KCNK3KMT2AMEN1KCNK9 | |
| SCHEMBL6579950 | 0.82 | NPC1 (0.73) | NR1H4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6580184 | 0.82 | NR1H4 (0.58) | NR1H4KMT2AMEN1KCNK9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |