Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577703 | 0.90 | PLK1 (0.64) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6580071 | 0.90 | PLK1 (0.58) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28418450 | 0.87 | PLK1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6577738 | 0.85 | NPC1 (0.63) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6580027 | 0.85 | F10 (0.66) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6581893 | 0.83 | BCHE (0.55) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6580473 | 0.83 | NR1H4 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6580051 | 0.83 | ALDH1A1 (0.57) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6580181 | 0.83 | MAPT (0.58) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6580254 | 0.83 | NR1H4 (0.53) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |