Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 4/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579934 | 0.87 | PLK1 (0.61) | TRPV1PLK1PLK3KDM4EABCG2 | |
| SCHEMBL6580460 | 0.85 | NPC1 (0.48) | SLC16A3KDM4ENPC1RAB9AGAA | |
| SCHEMBL6579964 | 0.84 | NPC1 (0.51) | HDAC1TRPV1KDM4ELMNANPC1 | |
| SCHEMBL6581823 | 0.84 | PLK1 (0.58) | NR1H4SLC16A3PPARAHDAC3HDAC1 | |
| SCHEMBL6577993 | 0.84 | PLK1 (0.61) | SLC16A3HDAC3HDAC1HDAC2TRPV1 | |
| SCHEMBL6580357 | 0.84 | NPC1 (0.55) | NR1H4SLC16A3KDM4ENPC1RAB9A | |
| SCHEMBL3381862 | 0.84 | POLB (0.56) | NR1H4HDAC3HDAC1HDAC2KDM4E | |
| SCHEMBL3377996 | 0.83 | NPC1 (0.59) | TRPV1KDM4ELMNANPC1RAB9A | |
| SCHEMBL6579947 | 0.83 | NPC1 (0.67) | PLK1KDM4ELMNANPC1RAB9A | |
| SCHEMBL6582795 | 0.82 | F10 (0.57) | HDAC3NCOR1HDAC1HDAC2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |