Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580152 | 1.00 | CETP (0.57) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL24074514 | 0.87 | CETP (0.65) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL27548637 | 0.87 | CETP (0.65) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL6580165 | 0.84 | KDM4E (0.53) | HDAC3HDAC1TSHRHDAC2HDAC4 | |
| SCHEMBL15894577 | 0.84 | EP300 (0.62) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL19004115 | 0.83 | CETP (0.59) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL3378244 | 0.82 | ALDH1A1 (0.51) | MAPK1LMNAKMT2ANPSR1 | |
| SCHEMBL30102565 | 0.82 | CETP (0.54) | CETPSOAT1EP300RXFP1TSHR | |
| SCHEMBL24420606 | 0.81 | CETP (0.63) | CETPSOAT1RXFP1TSHRMAPK1 | |
| SCHEMBL9395051 | 0.80 | CETP (0.77) | CETPSOAT1EP300HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |