Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582831 | 0.85 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL6577393 | 0.84 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4ELMNANLRP3 | |
| SCHEMBL6582795 | 0.81 | F10 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28926566 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4ELMNANLRP3 | |
| SCHEMBL6580027 | 0.80 | F10 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6580051 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL6581781 | 0.77 | KCNQ2 (0.60) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL6169126 | 0.77 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL3378244 | 0.76 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL16250677 | 0.74 | PARP14 (0.62) | ALDH1A1SMN1; SMN2KDM4ELMNANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |