Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651597 | 0.88 | HPGD (0.66) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6577393 | 0.87 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6582660 | 0.86 | KDM4E (0.63) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6581781 | 0.85 | KCNQ2 (0.60) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6580075 | 0.85 | ALDH1A1 (0.66) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPK8 | |
| SCHEMBL13602431 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL3378244 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6580165 | 0.81 | KDM4E (0.53) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6579874 | 0.81 | KDM4E (0.52) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL28926541 | 0.79 | HPGD (0.62) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |