Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16266096 | 0.86 | MEN1 (0.67) | ALDH1A1ADRB2BCL2KMT2AMEN1 | |
| SCHEMBL13852928 | 0.86 | ALDH1A1 (0.53) | ALDH1A1ADRB2BCL2KMT2AMEN1 | |
| SCHEMBL8971238 | 0.82 | ALDH1A1 (0.73) | ALDH1A1ADRB2BCL2KMT2AMEN1 | |
| SCHEMBL16266121 | 0.81 | NPC1 (0.53) | ALDH1A1ADRB2BCL2KMT2AMEN1 | |
| SCHEMBL6346822 | 0.81 | KCNK3 (0.71) | KMT2AMEN1KCNK3KCNK9PARP1 | |
| SCHEMBL31610160 | 0.77 | ALDH1A1 (0.51) | ALDH1A1ADRB2BCL2KMT2AMEN1 | |
| SCHEMBL14372335 | 0.77 | CA1 (0.60) | ALDH1A1KMT2AMEN1PKMRAB9A | |
| SCHEMBL8827735 | 0.76 | NR1H4 (0.59) | ALDH1A1KMT2AMEN1KCNK3KCNK9 | |
| SCHEMBL6577998 | 0.76 | NR1H4 (0.65) | ALDH1A1KMT2AMEN1KCNK3KCNK9 | |
| SCHEMBL6577802 | 0.76 | NR1H4 (0.62) | KMT2AMEN1KCNK3KCNK9PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |