SCHEMBL8971238

SCHEMBL8971238

O=C(Nc1ccccc1)c1ccccc1Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.73
ADRB2 P07550 1/20 0.73
BCAT2 O15382 1/20 0.68
BCL2 P10415 1/20 0.66
KDM4E B2RXH2 2/20 0.60
LMNA P02545 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HPGD P15428 2/20 0.59
CYP3A4 P08684 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
SGMS2 Q8NHU3 1/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
TP53 P04637 1/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.56
CAPN1 P07384 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
METAP2 P50579 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5238436 0.89 TSHR (0.65) ALDH1A1ADRB2BCAT2BCL2KDM4E
SCHEMBL5233758 0.88 TSHR (0.63) ALDH1A1ADRB2BCAT2BCL2KDM4E
SCHEMBL5236516 0.87 ALDH1A1 (0.57) ALDH1A1ADRB2BCAT2BCL2KDM4E
SCHEMBL28218260 0.87 ALDH1A1 (0.57) ALDH1A1ADRB2BCAT2BCL2KDM4E
SCHEMBL5233754 0.85 ALDH1A1 (0.56) ALDH1A1ADRB2BCAT2BCL2KDM4E
SCHEMBL6781102 0.85 RAB9A (0.66) ALDH1A1ADRB2KDM4ELMNASMN1; SMN2
SCHEMBL5232709 0.84 ALDH1A1 (0.63) ALDH1A1ADRB2KDM4ELMNASMN1; SMN2
SCHEMBL16266096 0.83 MEN1 (0.67) ALDH1A1ADRB2BCAT2BCL2KDM4E
SCHEMBL13852928 0.83 ALDH1A1 (0.53) ALDH1A1ADRB2BCAT2BCL2SMN1; SMN2
SCHEMBL6580091 0.82 ALDH1A1 (0.52) ALDH1A1ADRB2BCAT2BCL2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed