Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | CALCRL | Q16602 | 18/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063134 | 0.86 | CHRM2 (0.64) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL31192594 | 0.85 | CALCRL (0.55) | CALCRL | |
| SCHEMBL1197774 | 0.85 | CALCRL (0.55) | CALCRL | |
| SCHEMBL12087688 | 0.84 | CALCRL (0.61) | CALCRL | |
| SCHEMBL6577928 | 0.84 | CHRM1 (0.80) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2100682 | 0.83 | CALCRL (0.63) | CALCRL | |
| SCHEMBL1198682 | 0.82 | CALCRL (0.59) | CALCRL | |
| SCHEMBL13074126 | 0.82 | CALCRL (0.59) | CALCRL | |
| SCHEMBL29151374 | 0.82 | HCAR1 (0.53) | CALCRL | |
| SCHEMBL27829251 | 0.81 | CALCRL (0.58) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |